Riboflavin

Indication

It is used to prevent riboflavin deficiency, especially in patients with long-standing infections, liver disease, alcoholism, malignancy and those taking probenecid.

Dosage and Administration

Riboflavin deficiency:

Children: 2.5 - 10 mg/day in divided dose

Adult: 5 - 30 mg/day in divided dose

Composition

Each tablet contains:

Riboflavin B.P ... 10 mg.

Description

It is water soluble vitamin. Molecular formula of riboflavin is C17H20N406 and its molecular weight is 376.4.

Clinical Pharmacology

In humans, an exogenous source of riboflavin is required for tissue respiration. The coenzyme, riboflavin 5 phosphate acts as a hydrogen-carrier molecule for several enzymes (flavoproteins) involved in oxidation-reduction reactions of organic substrates and intermediary metabolism. It is also direct...read more

Pharmacokinetics

Riboflavin is absorbed from the gastrointestinal tract in the circulation, it is bound to plasma proteins. Excess of the body's requirements are excreted mainly in the urine.

Contraindication

Hypersensitivity to riboflavin (vitamin B2).

Precaution

Dosage is based on patients condition. Tell the doctors if the condition persists or worsen. Important counseling is needed for breastfeeding and pregnancy.

Adverse Effects

Large doses of riboflavin result in a bright yellow discoloration of the urine, which may interfere with certain laboratory tests.

Storage

Store below 30°C in cool, dry place. Protect from light and moisture. Keep out of reach and sight of children.

Presentation

20 x 10's Blisters, 100's Bottle.