Aspirin is indicated to reduce the risk of blood clots forming and thereby prevent further strokes, transient ischemic attacks (TIAs) and cardiovascular problems in patients who suffer from stable or unstable angina. It is also used in the treatment of acute heart attack and to prevent the formation...
One tablet to be taken once daily, preferably after meals or as prescribed by the physician.
Each tablet contains:
Aspirin B.P ... 80 mg.
Aspirin is non-selective cyclo-oxygenase inhibitor, antipyretic, analgesic, anti-inflammatory, anti-platelet. Chemically, it is 2-(Acetyloxy) benzoic acid. The molecular formula of aspirin is C9H8O4 and molecular weight is 108.2.
Aspirin irreversibly inhibits platelet COX so that anti-platelet effect of aspirin lasts 8-10 days (the life of platelet). In other tissues, synthesis of new COX replaces the inactivated enzyme so that ordinary doses have a duration of action of 6 - 12 hours. Aspirin, low dose antithrombotic agent, ...
Aspirin, Acetylsalicylic acid, is completely and rapidly absorbed from gastrointestinal tract. It is 80 to 90% bound to plasma protein. It is rapidly hydrolyzed (serum half-life is about 15 to 20 minutes) to acetic acid and salicylate by esterase in tissue and blood. It can pass through the breast m...
It is contraindicated in patients with history of hyper-sensitivity to aspirin, salicylates or any other NSAIDs; with asthma, angioedema, urticaria or rhinitis, gastritis, active peptic ulcer, bleeding disorder; children under 16 years and nursing mothers.
Administer with caution to patients with chronic renal insufficiency, gastric or peptic ulcers, erosive gastritis, severe liver or kidney problems, gout, preexisting hypoprothrombinemia and vitamin K deficiency. Aspirin should be used with caution in elderly patients who are prone to adverse events ...
Gastrointestinal disturbance such as nausea, dyspepsia and vomiting; irritation of gastric mucosa with erosion, ulceration, haematemesis and melaena; diarrhea, indigestion, increased tendency for bleeding; abnormal heavy or prolonged menstrual periods and bruising with purple spots (cutaneous bleedi...
Alcohol: Alcohol can increase risk of stomach bleeding caused by aspirin.
Anticoagulants: Aspirin may enhance hypoprothrombinemic effect of warfarin and other anticoagulants and increase risk of bleeding complication with these agents. Insulin and other hypoglycemic agents: Aspirin may increase the effect of oral hypoglycemics.
Uricosuric agents: Aspirin may interfere with uricosuric action of sulfinpyrazone, probenecid and phenylbutazone. Spironolactone: Sodium excretion produced by spironolactone may be decreased in the presence of salicylates. Corticosteroid: It may increase the risk of gastrointestinal ulceration and m...
Methotrexate: Severe bone marrow depression occurs when salicylates are administered with methotrexate.
Store below 30°C in cool and dry place. Protect from light and moisture. Keep out of reach and sight of children.
10 x 10’s Blisters.