Antimalarial drug for the treatment of uncomplicated malaria and multidrug resistant strain.
Adult : 3 tablets at once, daily for 3 consecutive days, taken at the same time each day (total dose - 9 tablets)
Children :(13 to< 24 kg):1 tablet daily for 3 consecutive days.
(24 to <36 kg): 2 tablets daily for 3 consecutive days.
Each film-coated tablet contains:
Dihydroartemisinin ... 50 mg
Piperaquine Phosphate ... 350 mg.
Dihydroartemisinin is very rapidly absorbed and the elimination half-life is approximately 1 hour. The dihydroartemisinin is highly active against both asexual and sexual forms of the four species of plasmodium.
Piperaquine, a highly lipophilic compound, is slowly absorbed and the elimination half-life is about 20 days. It pharmacokinetic profile as chloroquine phosphate.
It should not be used in pregnancy especially in first trimester and lactating mothers.
Cough, pyrexia, anaemia, headache, dizziness, nausea, anorexia, vomiting, diarrhoea, abdominal pain, QTc prolonged tachycardia.
10 x 9's blisters.